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Tag: ELISA kit

Reasons To Buy A Human IL-4 ELISA Kit

Interleukin-4 is a cytokine which induces differentiation in naive helper cells (Th0 to Th2 cells). The presence of IL-4 or IL-13, cytokines produced in a Th-2-type response, especially during allergy and parasitic infection, causes macrophages to become differentially activated. This cytokine acts as a ligand for the interleukin-4 receptor. Interleukin 4 receptor binds to IL13.

This may play a role in many of the overlapping functions of this cytokine with IL13. STAT6, which is a signal transducer/activator of transcription, plays a key role in the immune regulatory signal for this cytokine. You can buy high-quality human IL-4 Elisa kit via https://www.bosterbio.com/human-il-4-picokine-trade-elisa-kit-ek0404-boster.html.

 

Researchers recently discovered that IL-4, a cytokine, plays a crucial role in the development of innate CD8+ cells in the thymus in several gene-deficient mouse strains such as Itk, KLF2, CBP, and Id3, but without any previous exposure to antigen.

The Human IL-4 ELISA kit is an in vitro enzyme linked immunosorbent assay that measures the quantity of human IL-4 levels in serum, plasma and cell culture supernatants. IL-4 (Interleukin 4) a powerful lymphoid cell growth factor that stimulates certain B and T cells' growth and survival. It is a powerful anti-inflammatory factor that protects cells from intracellular pathogens. 

IL-4 plays a significant role in Th2 (T-helper cells) differentiation. It can also suppress pro-inflammatory mediators. Pemphigus is linked to IL-4. Mutations in this gene are linked to the risk of losing dental implants. Children might develop asthma or Mycoplasma pneumoniae infection from IL-4.

 

Know About GDNF ELISA Kit

GDNF or Glial Derived Neurotrophic factor Human ELISA (Enzyme Linked Immunosorbent Assay Kit) is an in-vitro enzyme link immunosorbent assay that measures the quantity of Human GDNF found in plasma and cells culture supernatants. This assay may not detect the human GDNF concentration in plasma.

The assay uses an antibody that is specific for Human GDNF and coated on a 96 well plate. The immobilized antibody is applied to the wells of the plates and the GDNF in the samples and standards are pipetted into them. After washing the wells, biotinylated anti Human GDNF antibody is added. You can buy top GDNF ELISA kit via Boster Bio.

The amount of GDNF bound to the color will affect the development of the color. The Stop Solution changes the color to yellow and measures the intensity at 450 nm. Only serum spiked with Human GDNF was able to detect the endogenous Human GDNF. Glial cell-line derived neurotrophic factors (GDNF), is a highly conserved member of the TGF Beta superfamily. 

The GDNF gene product can be processed into a disulphide linked homodimer that is a ligand to the RET proto oncogene. GDNF repairs and protects dopamine-containing neuronal cells that are degenerating in Parkinson's disease and motor neurons that die in amyotrophic lateral sclerosis. In the clinic, GDNF has been shown to be effective in treating Parkinson's disease. 

Neurological improvement has also been seen in the treatment of spinal cord injuries using GDNF. Human Glial Derived Neurotrophic Factor Hu or GDNF ELISA quantifies Hu GDNF levels in serum, plasma and cell culture media. This assay can only recognize natural and recombinant Hu GDNF. The microplate has wells that have been pre-coated with the target-specific antibody. 

 

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